讲师
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肖帅

作者:肖帅 时间:2022-03-22 浏览次数:

 

职称:讲师

学历:博士

联系方式:xiaoshuai825@hotmail.com

研究方向:细胞周期调控与肿瘤细胞衰老

学习工作经历:

2021年12月获得武汉大学理学博士学位;

2022年01月至今任教于湖北工业大学生物工程与食品学院

社会兼职:

中国细胞生物学学会会员,湖北省生物工程学会会员

科研项目:

2022年“武汉英才”优秀青年人才项目,2023.01-2025.12,主持

2022年湖北工业大学人才引进科研项目,XJ2022003901,2023.01-2025.12,主持

2023年国家自然科学基金面上项目,82370715,2024.01-2027.12,参与

2022年湖北省科技厅-国际科技合作项目,2022EHB038,2022.10-2024.9,参与

2022年武汉市曙光计划项目,2022010801020272,2022.06-2024.07,参与

2020年湖北省重点研发计划项目,2020BCB044,2020/09-2022/07,参与

2016年国家自然科学基金青年基金项目,31602095,2018.01-2019.12,参与

研究成果:

1. Xiao S,Qin DM, Hou XY, Tian LL, Yu YP, Zhang R, Lyu H, Guo D, Chen XZ, Zhou C, Tang JF.Cellular senescence: a double-edged sword in cancer therapy.Front Oncol2023. 13:1189015.

2. Xiao S,Hu D, Gao Y, Ai Y, Luo S, Chen S, Wang B, Zhou L, Dong Y, Wang Y. Safety assessment of subtilisin QK in rats.BMC Pharmacol Toxicol.2021; 22(1):38-49.

3. Xiao S, Dong Y, Hu K, Hu D, Zhou L, Wang Y. Acute and Subchronic Toxicities and Safety Pharmacology Studies of a Bacillus Subtilisin in Dogs.Biol Pharm Bull.2021; 44(2):211-218.

4. Zhou C, Zhu X, Liu N, Dong X, Zhang X, Huang H, Tang Y, Liu S, Hu M, Wang M, Deng X, Li S, Zhang R, Huang Y, Lyu H,Xiao S, Luo S, Ali DW, Michalak M, Chen XZ, Wang Z, Tang J. B-lymphoid tyrosine kinase-mediated FAM83A phosphorylation elevates pancreatic tumorigenesis through interacting with β-catenin.Signal Transduct Target Ther. 2023;8(1):66.

5. Zhang R, Yang Y, He C, Zhang X, Torraca V, Wang S, Liu N, Yang J, Liu S, Yuan J, Gou D, Li S, Dong X, Xie Y, He J, Bai H, Hu M, Liao Z, Huang Y, Lyu H,Xiao S,Guo D, Ali DW, Michalak M, Ma C, Chen XZ, Tang J, Zhou C.RUNDC1 inhibits autolysosome formation and survival of zebrafish via clasping ATG14-STX17-SNAP29 complex.Cell Death Differ. 2023,

6. Zhang X, Wu N, Huang H, Li S, Liu S, Zhang R, Huang Y, Lyu H,Xiao S, Ali DW, Marek M, Chen XZ, and Zhou C. Phosphorylated PTTG1 switches its subcellular distribution and promotes β-catenin stabilization and subsequent transcription activity,Oncogene, 2023,42(32):2439-2455.

7. Hu M, Zhang R, Yang J, Zhao C, Liu W, Huang Y, Lyu H,Xiao S, Guo D, Zhou C, Tang J. The role of N-glycosylation modification in the pathogenesis of liver cancer.Cell Death Dis. 2023, 29;14(3):222.

8. Hu D,Xiao S, Wang Y, Hua H.Notch is an alternative splicing gene in brown planthopper, Nilaparvata lugens.Arch Insect Biochem Physiol. 2022, 1: e21894.

9. Ai Y, Luo S, Wang B,Xiao S, Wang Y. MiR-126-5p Promotes Tumor Cell Proliferation, Metastasis and Invasion by Targeting TDO2 in Hepatocellular Carcinoma.Molecules. 2022; 27(2):443.

10. Luo S,Xiao S,Ai Y,Wang B,Wang Y. Changes in the hepatic differentiation potential of human mesenchymal.Annals of Translational Medicine. 2021, 9(21):1628.

11. Ai Y, Wang B,Xiao S, Luo S, Wang Y. Tryptophan Side-Chain Oxidase Enzyme Suppresses Hepatocellular Carcinoma Growth through Degradation of Tryptophan.International Journal of Molecular Sciences.2021; 22(22):12428.

12. Luo S, Ai Y,Xiao S, Wang B, Wang Y. Functional hit 1 (FH1)-based rapid and efficient generation of functional hepatocytes from human mesenchymal stem cells: a novel strategy for hepatic differentiation.Annals of Translational Medicine.2021;9(13):1087.

13. Liu X, Fang Y, Zhou P, Lu Y, Zhang Q,Xiao S, Dong Z, Pan L, Lv J, Zhang Z, Zhang Y, Wang Y. Chimeric virus-like particles elicit protective immunity against serotype O foot-and-mouth disease virus in guinea pigs.Applied Microbiology and Biotechnology.2017; 101(12):4905-4914.

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