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郭 冬

作者:郭冬 时间:2022-09-28 浏览次数:

 

职  称:讲师

学  历:博士

E-mailm13006386336@163.com

研究方向:基于CRISPR高通量筛选技术进行肿瘤相关致病机制与药物靶点的研究

学习工作经历:

    20169月至20226月:  武汉大学,微生物学(医学病毒学方向),理学博士学位

    20228月至今:         湖北工业大学,生物工程与食品学院细胞调控与分子药物团队,讲师

研究成果:

1. Guo Dong, Yu Xinghai, Wang Dan, Li Zhifei, ZhouYu, Xu Guodong, Yuan Bing, Qin Yali, Chen Mingzhou. SLC35B2 acts in a dual role in the host sulfation required for EV71 infection. Journal of Virology, 2022, 96 (9): e02042-02021.

2. Wang Dehe, Jiang Ao, Feng Jiangpeng, Li Guangnan, Guo Dong, Sajid Muhammad, Wu Kai, Zhang Qiuhan, Ponty Yann, Will Sebastian, Liu Feiyan, Yu Xinghai, Li Shaopeng, Liu Qianyun, Yang Xing-Lou, Guo Ming, Li Xingqiao., Chen Mingzhou, Shi Zheng-Li, Lan Ke, Chen Yu, Zhou Yu. The SARS-CoV-2 subgenome landscape and its novel regulatory features. Molecular Cell, 2021, 81 (10): 2135-2147.

3. Liu Xinjin, Feng Jiangpeng, Zhang Qiuhan, Guo Dong, Zhang Lu, Suo Tao, Hu Wenjia, Guo Ming, Wang Xin, Huang Zhixiang, Xiong Yong, Chen Guozhong, Chen Yu, Lan Ke. Analytical comparisons of SARS-CoV-2 detection by qRT-PCR and ddPCR with multiple primer/probe sets. Emerging Microbes & Infections, 2020, 9 (1): 1175-1179.

4. Li Zhifei, Guo Duo, Qin Yali, Chen Mingzhou. PI4KB on inclusion bodies formed by ER membrane remodeling facilitates replication of human parainfluenza virus type 3. Cell Reports, 2019, 29 (8): 2229-2242.

5. Suo Tao, Liu Xinjin, Feng Jiangpeng, Guo Ming, Hu Wenjia, Guo Dong, Ullah Hafiz, Yang Yang, Zhang Qiuhan, Wang Xin, Sajid Muhammad, Huang Zhixiang, Deng Liping, Chen Tielong, Liu Fang, Xu Ke, Liu Yuan, Zhang Qi, Liu Yingle, Xiong Yong, Chen Guozhong, Lan Ke, Chen Yu. ddPCR: a more accurate tool for SARS-CoV-2 detection in low viral load specimens. Emerging Microbes & Infections, 2020, 9 (1): 1259-1268.

6. Xiong Yong, Liu Yuan, Cao Liu, Wang Dehe, Guo Ming, Jiang Aa, Guo Dong, Hu Wenjia, Yang Jiayi, Tang Zhidong, Wu Honglong, Lin Yongquan, Zhang Meiyuan, Zhang Qi, Shi Mang, Liu Yingle, Zhou Yu, Lan Ke, Chen Yu. Transcriptomic characteristics of bronchoalveolar lavage fluid and peripheral blood mononuclear cells in COVID-19 patients. Emerging Microbes & Infections, 2020, 9 (1): 761-770.

7. Yang Xiaodan, Hu Zhulong, Zhang Qiang, Fan Shanshan, Zhong Yi, Guo Dong, Qin Yali, Chen Mingzhou. SG formation relies on eIF4GI-G3BP interaction which is targeted by picornavirus stress antagonists. Cell Discovery, 2019, 5 (1): 1-14.

8. Yang Xiaodan, Hu Zhulong, Fan Shanshan, Zhang Qiang, Zhong Yi, Guo Dong, Qin Yali, Chen Mingzhou. Picornavirus 2A protease regulates stress granule formation to facilitate viral translation. PLoS Pathogens, 2018, 14 (2): e1006901.

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