职 称：讲师

学 历：博士

E-mail:drzhougao@foxmail.com

研究方向：中药及天然产物的活性研究及功能开发

工作经历：

2009年9月-2013年6月 就读于武汉大学药学院药学专业，获学士学位；

2013年9月-2020年6月 就读于武汉大学药学院，获生物化学与分子生物学专业博士；

2020年7月-至今 湖北工业大学生物工程与食品学院

研究课题：

1、国家科技支撑计划、2012BA129B03、中药标本资源保存及网络化共享关键技术研究、2012/01-2017/1、已结题、参与；

2、国家科技支撑计划、2011BAI06B03-2、茯苓质量评价体系研究及荷曲胶囊的研制开发、2011/01-2016/12、已结题、参与；

3、国家科技支撑计划、2011BAI06B03-1、厚朴GAP基地及其SOP优化升级研究、2011/01-2016/12、已结题、参与。

研究成果：

1. Lin. Chen, Zhou, Gao, Xiao-Shan Meng, Hui-Ying Fu，Qigui. Mo, and Youwei. Wang, Photoprotection of maqui berry against ultraviolet B-induced photodamage in vitro and in vivo. Food Funct., 2020, 11, 2749-2762 (Co-first author)

2. Zhou, Gao, Lin. Chen, Qin. Sun, Qigui. Mo, Wanchun. Sun and Youwei. Wang, Maqui berry exhibited therapeutic effects against DSS-induced ulcerative colitis in C57BL/6 mice. Food Funct., 2019, 10, 6655-6665 (Co-first author)

3.Chen, Yuxin & Zhou, Gao & Ma, Bingxin & Tong, Jing & Wang, Youwei. (2019). Active Constituent in the Ethyl Acetate Extract Fraction of Terminalia bellirica Fruit Exhibits Antioxidation, Antifibrosis, and Proapoptosis Capabilities In Vitro. Oxidative Medicine and Cellular Longevity. 2019. 1-15. (Co-first author)

4. Gao Zhou, Yuxin Chen, Song Liu, Xingcheng Yao, Youwei Wang. In vitro and in vivo hepatoprotective and antioxidant activity of ethanolic extract from Meconopsis integrifolia (Maxim.) Franch. Journal of Ethnopharmacology 2013, 148: 664-670.

5. Y. Chen, Z. Zhou, Q. Mo, G. Zhou, Y. Wang, Gallic Acid Attenuates Dimethylnitrosamine-Induced Liver Fibrosis by Alteration of Smad Phosphoiso form Signaling in Rats. BioMed Research International.2018. 1682743.

6. Ma, B., Meng, X., Tong, J., Ge, L., Zhou, G., & Wang, Y. (2018). Protective effects of coptis chinensis inflorescence extract and linarin against carbon tetrachloride-induced damage in hepg2 cells through the mapk/keap1-nrf2 pathway. Food & Function, 10.1039. C8FO00078F.

7. Lanlan Ge, Ling Chen, Qigui Mo, Gao Zhou, Xiaoshan Meng, & Youwei Wang. (2018). Total phenylethanoid glycosides and magnoloside i a from magnolia officinalis var. biloba fruits inhibit ultraviolet b-induced phototoxicity and inflammation through mapk/nf-κb signaling pathways. RSC Advances, 8.

8. Ge, L., Zhang, W., Zhou, G., Ma, B., Mo, Q., & Chen, Y., et al. (2017). Nine phenylethanoid glycosides from magnolia officinalis var. biloba fruits and their protective effects against free radical-induced oxidative damage. Scientific Reports, 7, 45342.

9. Hu, Shu Hua, G. Zhou, and Y. W. Wang. "Tyrosinase Inhibitory Activity of Total Triterpenes and Poricoic Acid A Isolated from, Poria cocos." Chinese Herbal Medicines 9.4(2017):321-327.

10. Ma, B. , Wang, J. , Tong, J. , Zhou, G. , Chen, Y. , & He, J. , et al. (2016). Protective effects of chaenomeles thibetica extract against carbon tetrachloride-induced damage via the mapk/nrf2 pathway. Food & Function, 7.

11. Tong, J. , Mo, Q. G. , Ma, B. X. , Ge, L. L. , Zhou, G. , & Wang, Y. W. . (2016). The protective effects of cichorium glandulosum seed and cynarin on cyclophosphamide and its metabolite acrolein-induced hepatotoxicity in vivo and in vitro. Food & Function, 8(1), 209.

12. Ma, B. , Tong, J. , Zhou, G. , Mo, Q. , He, J. , & Wang, Y. . (2016). Coptis chinensis inflorescence ameliorates hyperglycaemia in 3t3-l1 preadipocyte and streptozotocin-induced diabetic mice. Journal of Functional Foods, 21, 455-462.

13. Tong, J. , Yao, X. , Zeng, H. , Zhou, G. , Chen, Y. , & Ma, B. , et al. (2015). Hepatoprotective activity of flavonoids from cichorium glandulosum seeds in vitro and in vivo carbon tetrachloride-induced hepatotoxicity. Journal of Ethnopharmacology.

14. Tong, J. , Ma, B. , Ge, L. , Mo, Q. , Zhou, G. , & He, J. , et al. (2015). Dicaffeoylquinic acid-enriched fraction of\r, cichorium glandulosum\r, seeds attenuates experimental type 1 diabetes via multipathway protection. Journal of Agricultural and Food Chemistry, 63(50), 10791-10802.

15. Bo Huang, Yuxin Chen, Bingxin Ma, Gao Zhou, Jing Tong, Jingsheng He, Youwei Wang. Protective effect of Cichorium glandulosum seeds from ultraviolet B-induced damage in rat liver mitochondria. Food & Function 2014, 5: 869-875.

16.周高,张文慧,莫启贵,王有为.厚朴中6种苯丙素类化合物的含量及其功效[J].武汉大学学报(理学版),2019,65(04):340-346.